98% by TLC [10% CH3OH in CH2Cl2, Rf = 0.25] NMR (Conforms)
Form:
Yellow solid
CAS Number:
[152121-30-7]
Formula:
C20H14N3OF
Application Notes:
Potent and selective p38 MAP kinase inhibitor acting at the ATP site1. Selectively inhibits the p38alpha and beta isoforms (IC50= 50 and 100 nM for SAPK2a/p38 and SAPK2b/p38beta2 respectively)2. Effectively blocks LPS-induced gene expression in monocytes3. Induces
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