Sorafenib (base), CAS [[284461-73-0]]
Catalog Number:
FBM-10-2174
| Article Name: |
Sorafenib (base), CAS [[284461-73-0]] |
| Biozol Catalog Number: |
FBM-10-2174 |
| Supplier Catalog Number: |
10-2174 |
| Alternative Catalog Number: |
FBM-10-2174-10MG,FBM-10-2174-50MG |
| Manufacturer: |
Focus Biomolecules |
| Category: |
Biochemikalien |
| Alternative Names: |
BAY 43-9006 |
| Raf-1 inhibitor (and other kinases) |
| Molecular Weight: |
464.83 |
| Purity: |
99% by TLC, NMR (Conforms) |
| Form: |
Off-white solid |
| CAS Number: |
[284461-73-0] |
| Formula: |
C21H16ClF3N4O3 |
| Application Notes: |
Initially developed as a Raf kinase inhibitor, IC50 = 6 nM, but has been shown to inhibit many receptor tyrosine kinases including BRAF (IC50 = 22 nM), VEGFR-2 (IC50 = 90 nM), VEGFR-3 (IC50 = 20 nM), PDGFR-beta (IC50 = 57 nM), Flt3 (IC50 = 58 nM), c-KIT (IC |
