Tofacitinib, CAS [[477600-75-2]]

Product Overview

• Article Name: Tofacitinib, CAS [[477600-75-2]]
• Biozol Catalog Number: FBM-10-2177
• Supplier Catalog Number: 10-2177
• Alternative Catalog Number: FBM-10-2177-5MG,FBM-10-2177-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Tasocitinib, CP-690550

Product Description

JAK inhibitor

Product Properties

• Molecular Weight: 312.37
• Purity: 99% by HPLC and TLC NMR (conforms)
• Form: Off-white solid
• CAS Number: [477600-75-2]
• Formula: C16H20N6O

Application Notes

• Application Notes: Potent pan-JAK inhibitor, IC50s=1, 20 and 112 nM for JAK3, JAK2 and JAK1 respectively.1 Displays potent antiinflammatory2 and immunosuppressant3 activity. Promotes a white-to-brown metabolic metabolic conversion in human adipoctes.4 In therapeutic use fo