Vismodegib, CAS [[879085-55-9]]

Product Overview

• Article Name: Vismodegib, CAS [[879085-55-9]]
• Biozol Catalog Number: FBM-10-2182
• Supplier Catalog Number: 10-2182
• Alternative Catalog Number: FBM-10-2182-5MG,FBM-10-2182-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: GDC-0449

Product Description

Sonic Hedgehog signaling pathway inhibitor

Product Properties

• Molecular Weight: 421.30
• Purity: 99% by TLC and HPLC NMR (Conforms)
• Form: Off-white or beige solid
• CAS Number: [879085-55-9]
• Formula: C19H14Cl2N2O3S

Application Notes

• Application Notes: A potent and selective Hedgehog (Hh) pathway signaling inhibitor antagonizing SMO with a Ki of 1.3 nM).1 Alters intracellular Ca2+ homeostasis and inhibits growth of cisplatin-resistant lung cancer cells.2 Inhibits two ABC transporters, ABCG2/BCRP and AB