Picropodophyllotoxin, CAS [[477-47-4]]

Product Overview

• Article Name: Picropodophyllotoxin, CAS [[477-47-4]]
• Biozol Catalog Number: FBM-10-2189
• Supplier Catalog Number: 10-2189
• Alternative Catalog Number: FBM-10-2189-5MG,FBM-10-2189-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

IGF1R inhibitor

Product Properties

• Molecular Weight: 414.42
• Purity: 97% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [477-47-4]
• Formula: C22 H22 O8

Application Notes

• Application Notes: Potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP1. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM1. Displays antiproliferative activity in n