Veliparib 2HCl, CAS [[912445-05-7]]

Product Overview

• Article Name: Veliparib 2HCl, CAS [[912445-05-7]]
• Biozol Catalog Number: FBM-10-2419
• Supplier Catalog Number: 10-2419
• Alternative Catalog Number: FBM-10-2419-5MG,FBM-10-2419-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: ABT-888

Product Description

PARP 1&2 inhibitor

Product Properties

• Molecular Weight: 317.22
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [912445-05-7]
• Formula: C13H16N4O2HCl

Application Notes

• Application Notes: Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometr