SN-38, CAS [[86639-52-3]]

Product Overview

• Article Name: SN-38, CAS [[86639-52-3]]
• Biozol Catalog Number: FBM-10-2425
• Supplier Catalog Number: 10-2425
• Alternative Catalog Number: FBM-10-2425-10MG,FBM-10-2425-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

DNA topoisomerase I inhibitor

Product Properties

• Molecular Weight: 392.41
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [86639-52-3]
• Formula: C22H20N2O5

Application Notes

• Application Notes: Active metabolite of CPT-11 that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 µM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 µM respectively) but does not affect protein synthesis.