Leukotriene CysLT1 antagonist and GPR17 antagonist
Molecular Weight:
481.51
Purity:
98%, NMR (Conforms)
Form:
White solid
CAS Number:
[103177-37-3]
Formula:
C27H23N5O4
Application Notes:
Pranlukast is a selective Leukotriene CysLT1 antagonist1 and has been used in the treatment of asthma2. Pranlukast is also an inhibitor of GPR173 (IC50s = 10.5nM hGPR17, 31nM rGPR17) and is superior to Montelukast in achieving functional inhibition4.
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