Topotecan HCl, CAS [[119413-54-6]]

Catalog Number: FBM-10-2479
Article Name: Topotecan HCl, CAS [[119413-54-6]]
Biozol Catalog Number: FBM-10-2479
Supplier Catalog Number: 10-2479
Alternative Catalog Number: FBM-10-2479-10MG,FBM-10-2479-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: NSC 609669, SKF-104864A
DNA topoisomerase I inhibitor
Molecular Weight: 457.91
Purity: >98% by HPLC NMR (Conforms)
Form: Yellow solid
CAS Number: [119413-54-6]
Formula: C23H23N3O5 HCl
Application Notes: Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN