Phosphoramidon, CAS [[119942-99-3]]
Catalog Number:
FBM-10-2548
Article Name: |
Phosphoramidon, CAS [[119942-99-3]] |
Biozol Catalog Number: |
FBM-10-2548 |
Supplier Catalog Number: |
10-2548 |
Alternative Catalog Number: |
FBM-10-2548-5MG,FBM-10-2548-25MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Neutral endopeptidase inhibitor |
Molecular Weight: |
587.47 |
Purity: |
97% by TLC NMR (Conforms) |
Form: |
White solid |
CAS Number: |
[119942-99-3] |
Formula: |
C23H32N3O10P2Na |
Application Notes: |
Inhibits neutral endopeptidase 24.11 (NEP, Neprilysin, EC 3.4.24.11), Ki=2 nM.1 Also inhibits neprilysin 2 (Ki~2 nM).2 Also inhibits endothelin-converting enzyme (IC50 = 0.68 µM).3 Induces a dramatic increase in amyloid-beta levels in rodents.4 |