PP242, CAS [[1092351-67-1]]

Product Overview

• Article Name: PP242, CAS [[1092351-67-1]]
• Biozol Catalog Number: FBM-10-2695
• Supplier Catalog Number: 10-2695
• Alternative Catalog Number: FBM-10-2695-5MG,FBM-10-2695-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Torkinib

Product Description

Dual mTORC1/mTORC2 inhibitor

Product Properties

• Molecular Weight: 308.35
• Purity: >98% by HPLC NMR (Conforms)
• Form: Off-white to beige solid
• CAS Number: [1092351-67-1]
• Formula: C16H16N6O

Application Notes

• Application Notes: PP242 is an ATP-competitive mTORC1/mTORC2 inhibitor (IC50 = 8 nM) displaying high selectivity over PI 3K family kinases (IC50s =0.102 to 2.2 µM) and modest selectivity over PKC family kinases (IC50s =0.049 to 0.198 µM).1,2 PP 242 (but not rapamycin) indu