PLX-4032, CAS [[918504-65-1]]

Product Overview

• Article Name: PLX-4032, CAS [[918504-65-1]]
• Biozol Catalog Number: FBM-10-2928
• Supplier Catalog Number: 10-2928
• Alternative Catalog Number: FBM-10-2928-5MG,FBM-10-2928-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Vemurafenib, R7204, Ro 51-85426

Product Description

BRAF inhibitor

Product Properties

• Molecular Weight: 489.92
• Purity: 99% by HPLC, NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [918504-65-1]
• Formula: C23H18ClF2N3O3S

Application Notes

• Application Notes: An ATP-competitive inhibitor of mutant V600E/F and wild type B-Raf, IC50s=31 and 100 nM respectively.1 Induced growth inhibition, G0/G1 arrest and apoptosis in a variety of cancer cell lines, with a B-Raf mutation favoring but not guaranteeing a response