Cabozantinib, CAS [[849217-68-1]]

Product Overview

• Article Name: Cabozantinib, CAS [[849217-68-1]]
• Biozol Catalog Number: FBM-10-3231
• Supplier Catalog Number: 10-3231
• Alternative Catalog Number: FBM-10-3231-5MG,FBM-10-3231-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: XL-184, BMS-907351,

Product Description

Met and VEGFR2 inhibitor

Product Properties

• Molecular Weight: 501.51
• Purity: 98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [849217-68-1]
• Formula: C28H24FN3O5

Application Notes

• Application Notes: Novel inhibitor of c-met and VEGFR2 kinase activity, IC50=3.5 nm and 35 pM respectively.1 Inhibits MET-activating kinase domain mutations Y1248H, D1246N or K1262R, IC50=3.8, 11.8 and 14.6 nM respectively. In cellular assays it inhibits the following kina