Nintedanib, CAS [[656247-17-5]]

Product Overview

• Article Name: Nintedanib, CAS [[656247-17-5]]
• Biozol Catalog Number: FBM-10-3320
• Supplier Catalog Number: 10-3320
• Alternative Catalog Number: FBM-10-3320-10MG,FBM-10-3320-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: BIBF-1120

Product Description

VEGFR, PDGFR and FGFR kinase inhibitor

Product Properties

• Molecular Weight: 539.64
• Purity: >98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [656247-17-5]
• Formula: C31H33N5O4

Application Notes

• Application Notes: Nintedanib is a potent inhibitor of VEGFR, PDGFR, FGFR (IC50 = 13-34 nM for VEGFR, 59-65 nM for PDGFR and 37-108 nM for FGFR subtypes).1 Also inhibits Flt-3, Lck, Lyn and Src (IC50 = 16-156 nM). Inhibits VEGF-stimulated proliferation of HUVECs.1 Inhibits