Koningic acid, CAS [[74310-84-2]]

Product Overview

• Article Name: Koningic acid, CAS [[74310-84-2]]
• Biozol Catalog Number: FBM-10-3326
• Supplier Catalog Number: 10-3326
• Alternative Catalog Number: FBM-10-3326-1MG,FBM-10-3326-2.5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Heptelidic acid, BRN5091359, Avocettin

Product Description

Glyceraldehyde-3-phosphate dehydrogenase inhibitor

Product Properties

• Molecular Weight: 280.32
• Purity: 95% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [74310-84-2]
• Formula: C15H20O5

Application Notes

• Application Notes: Koningic acid (KA) is a potent and selective inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH).1 Inhibition is irreversible and proceeds via nucleophilic attack of an active site cysteine on the epoxide moiety2, Ki = 1.1 µM for rabbit muscle