4,9-Anhydro-tetrodotoxin, CAS [[13072-89-4]]
Catalog Number:
FBM-10-3700
Article Name: |
4,9-Anhydro-tetrodotoxin, CAS [[13072-89-4]] |
Biozol Catalog Number: |
FBM-10-3700 |
Supplier Catalog Number: |
10-3700 |
Alternative Catalog Number: |
FBM-10-3700-100UG,FBM-10-3700-1MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Selective sodium channel blocker |
Molecular Weight: |
301.25 |
Purity: |
>98% by HPLC : [1% acetonitrile / 0.05M NH4OAc, 0.5 ml/min, Luna C18, ELSD detection], NMR: Conforms High Res Mass: Conforms |
Form: |
Colorless film |
CAS Number: |
[13072-89-4] |
Formula: |
C11H15N3O7 |
Application Notes: |
4,9-Anhydrotetrodotoxin is a highly selective blocker of the Na(v1.6) sodium channel. (IC50s: Na(v1.2) = 260 nM, Na(v1.3) = 341 nM, Na(v1.4) = 988 nM, Na(v1.5) = 11.6 µM, Na(v1.6) = 7.8 nM, Na(v1.7) = 1.27 µM, Na(v1.8) = >30 µM.).1 |