Ranolazine, CAS [[142387-99-3]]

Product Overview

• Article Name: Ranolazine, CAS [[142387-99-3]]
• Biozol Catalog Number: FBM-10-3701
• Supplier Catalog Number: 10-3701
• Alternative Catalog Number: FBM-10-3701-10MG,FBM-10-3701-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Selective sodium channel blocker

Product Properties

• Molecular Weight: 427.54
• Purity: 98% by TLC (10% methanol/methylene chloride, Rf = 0.63)
• Form: White solid
• CAS Number: [142387-99-3]
• Formula: C24H33N3O4

Application Notes

• Application Notes: Ranolazine is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels.1 It blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50s = 2.42, 6.22, 1.72(10.