Potent inhibitor of steroid receptor coactivator-3 (SRC-3)
Molecular Weight:
265.31
Purity:
98% by HPLC NMR (Conforms)
Form:
Pale orange solid
CAS Number:
[380537-35-9]
Formula:
C15H15N5
Application Notes:
Si-2 is a potent inhibitor of steroid receptor coactivator-3 (SRC-3).1 It blocks MDA-MB-468 cell growth with an IC50 = 3.4 nM without effecting normal cells.1 It significantly inhibited breast cancer cell growth in an orthotopic MDA-MD-468 mouse model. T
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