CIB-3b, CAS [[124811-87-6]]

Product Overview

• Article Name: CIB-3b, CAS [[124811-87-6]]
• Biozol Catalog Number: FBM-10-3923
• Supplier Catalog Number: 10-3923
• Alternative Catalog Number: FBM-10-3923-5MG,FBM-10-3923-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Inhibitor of microRNA biogenesis

Product Properties

• Molecular Weight: 261.28
• Purity: >98% by HPLC , NMR (Conforms)
• Form: White solid
• CAS Number: [124811-87-6]
• Formula: C14H15NO4

Application Notes

• Application Notes: CIB-3b inhibits microRNA (miRNA) biogenesis via binding (KD = 10.42 nM) to transactivation response (TAR) RNA-binding protein 2 (TRBP), disrupting the TRBP-Dicer interaction, a critical element in pre-miRNA processing. It inhibited mi-R21 (EC50 = 1.38 µM