Trametiglue, CAS [[2666940-97-0]]

Product Overview

• Article Name: Trametiglue, CAS [[2666940-97-0]]
• Biozol Catalog Number: FBM-10-3961
• Supplier Catalog Number: 10-3961
• Alternative Catalog Number: FBM-10-3961-5MG, FBM-10-3961-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: APS-9-95-1

Product Description

MEK inhibitor / molecular glue

Product Properties

• Molecular Weight: 666.47
• Purity: >98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [2666940-97-0]
• Formula: C25H24FIN6O5S

Application Notes

• Application Notes: Trametiglue is a trametinib analog that inhibits both KSR- and RAF-bound MEK and limits adaptive resistance seen with trametinib via enhanced interfacial binding. Displays significantly enhanced inhibition of RAS/ERK signaling versus trametinib is variou