PT-179, CAS [[2924858-25-1]]

Product Overview

• Article Name: PT-179, CAS [[2924858-25-1]]
• Biozol Catalog Number: FBM-10-3963
• Supplier Catalog Number: 10-3963
• Alternative Catalog Number: FBM-10-3963-5MG, FBM-10-3963-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Thalidomide analog molecular glue

Product Properties

• Molecular Weight: 343.34
• Purity: >98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [2924858-25-1]
• Formula: C17 H17N3O5

Application Notes

• Application Notes: PT-179 is an orthogonal thalidomide analog that binds cereblon (CRBN: KD = 587 nM, pomalidomide KD = 500 nM) with greatly reduced off-target activity compared to pomalidomide. Pomalidomide induced differential expression of 1426 genes in MM.1S multiple m