PF-05089771, CAS [[1235403-62-9]]

Product Overview

• Article Name: PF-05089771, CAS [[1235403-62-9]]
• Biozol Catalog Number: FBM-10-3990
• Supplier Catalog Number: 10-3990
• Alternative Catalog Number: FBM-10-3990-5MG,FBM-10-3990-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: PF771

Product Description

Selective Nav1.7 channel blocker

Product Properties

• Molecular Weight: 500.34
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1235403-62-9]
• Formula: C18H12Cl2FN5O3S2

Application Notes

• Application Notes: Potent and selective inhibitor of the voltage gated sodium channel 1.7 (Nav1.7).1,3 It is a state-dependent inhibitor with IC50 = 11 nM for the half-inactivated channels and IC50 ~ 10 µM for resting channels.1 Equipotent for human, monkey, dog, and mouse