SP100030, CAS [[154563-54-9]]

Product Overview

• Article Name: SP100030, CAS [[154563-54-9]]
• Biozol Catalog Number: FBM-10-3996
• Supplier Catalog Number: 10-3996
• Alternative Catalog Number: FBM-10-3996-5MG, FBM-10-3996-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: 2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3,5-bis(trifluoromethyl)phenyl)carboxamide

Product Description

Dual NF-kB / AP-1 inhibitor

Product Properties

• Molecular Weight: 437.65
• Purity: >98% by HPLC, NMR (conforms)
• Form: Off-white solid
• CAS Number: [154563-54-9]
• Formula: C14H5ClF9N3O

Application Notes

• Application Notes: SP100030 is a potent dual inhibitor of NF-kB- and AP-1-mediated gene expression (IC50s = 50 nM for both in transfected Jurkat T-cells).1 It was able to specifically block IL-2 and IL-8 in Jurkat T-cells (IC50s = 30 nM for both).1 SP100030 treatment sig