QNZ, CAS [[545380-34-5]]

Product Overview

• Article Name: QNZ, CAS [[545380-34-5]]
• Biozol Catalog Number: FBM-10-4009
• Supplier Catalog Number: 10-4009
• Alternative Catalog Number: FBM-10-4009-5MG,FBM-10-4009-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: EVP4593

Product Description

NFkB inhibitor / Store-operated calcium entry

Product Properties

• Molecular Weight: 356.42
• Purity: 98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [545380-34-5]
• Formula: C22H20N4O

Application Notes

• Application Notes: QNZ was originally described as a potent inhibitor of NF-B activation (IC50 = 11 n) and TNF- production (IC50 = 7 nM).1,2 It indirectly inhibits the NF-B pathway via inhibition of store-operated calcium entry (SOC) and displayed neuroprotective effect