URMC-099, CAS [[1229582-33-5]]

Product Overview

• Article Name: URMC-099, CAS [[1229582-33-5]]
• Biozol Catalog Number: FBM-10-4012
• Supplier Catalog Number: 10-4012
• Alternative Catalog Number: FBM-10-4012-5MG,FBM-10-4012-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Mixed-lineage kinase 3 inhibitor

Product Properties

• Molecular Weight: 421.54
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1229582-33-5]
• Formula: C27H27N5

Application Notes

• Application Notes: URMC-099 is a potent (IC50 = 14 nM), brain penetrant mixed-lineage kinase 3 inhibitor (MLK3). It also potently inhibits FLT3 (4 nM in vitro, but 560 nM in vivo), LRRK2 (11 nM), and ABL1 (3 nM).1 URMC-099 displayed neuroprotective effects in HIV-associate