Lomeguatrib, CAS [[192441-08-0]]

Product Overview

• Article Name: Lomeguatrib, CAS [[192441-08-0]]
• Biozol Catalog Number: FBM-10-4017
• Supplier Catalog Number: 10-4017
• Alternative Catalog Number: FBM-10-4017-10MG,FBM-10-4017-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: O6-(4-Bromothenyl)guanine

Product Description

MGMT inhibitor

Product Properties

• Molecular Weight: 326.17
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white or beige solid
• CAS Number: [192441-08-0]
• Formula: C10H8BrN5O3S

Application Notes

• Application Notes: Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as wel