GSK3326595, CAS [[1616392-22-3]]

Product Overview

• Article Name: GSK3326595, CAS [[1616392-22-3]]
• Biozol Catalog Number: FBM-10-4028
• Supplier Catalog Number: 10-4028
• Alternative Catalog Number: FBM-10-4028-5MG,FBM-10-4028-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: EPZ015938

Product Description

PRMT5 inhibitor

Product Properties

• Molecular Weight: 452.56
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1616392-22-3]
• Formula: C24H32N6O3

Application Notes

• Application Notes: GSK3326595 is a potent (IC50 = 6.2nM), selective (>4000-fold over 20 other methyltransferases), SAM uncompetitive, peptide competitive inhibitor of PRMT5.1 PRMT5 inhibition activated the p53 pathway via induction of alternative splicing of MDM4 leading t