CPI-455, CAS [[1628208-23-0]]

Catalog Number: FBM-10-4035
Article Name: CPI-455, CAS [[1628208-23-0]]
Biozol Catalog Number: FBM-10-4035
Supplier Catalog Number: 10-4035
Alternative Catalog Number: FBM-10-4035-5MG,FBM-10-4035-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Lysine demethylase KDM5 inhibitor
Molecular Weight: 278.32
Purity: 98% by HPLC NMR (conforms)
Form: Off-white solid
CAS Number: [1628208-23-0]
Formula: C16H14N4O
Application Notes: CPI-455 (1628208-23-0) is a potent (IC50 = 10 nM) and selective inhibitor of the lysine demethylase KDM5 (equal inhibition of KDM5A, 5B, 5C).1 CPI-455 reduced the number of drug-tolerant persister cancer cells (DTPs) in a dose-dependent, KDM5-dependent m