Inhibitor of the H2AK119 deubiquitinase BAP1 (IC50 = 0.092 µg/ml). It is selective for BAP1 over UCHL5, USP5,7,8, TNFAIP3-catalytic domain, USP2-catalytic domain, Otubain-1, and Ataxin3. iBAP-II disrupted the BAP1/ASXL3/BRD4 axis via induction of protein
* VAT and and shipping costs not included. Errors and price changes excepted