TETi76 ester, CAS [[1451750-73-4]]

Catalog Number: FBM-10-4041
Article Name: TETi76 ester, CAS [[1451750-73-4]]
Biozol Catalog Number: FBM-10-4041
Supplier Catalog Number: 10-4041
Alternative Catalog Number: FBM-10-4041-10MG,FBM-10-4041-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
TET inhibitor
Molecular Weight: 216.23
Purity: >98% TLC, NMR (Conforms)
Form: Colorless oil
CAS Number: [1451750-73-4]
Formula: C10H16O5
Application Notes: Cell permeable inhibitor of TET dioxygenases (IC50s: TET1 = 1.5 µM, TET2 = 9.4 µM, TET3 = 8.8 µM), indirect (via cytosine hydroxymethylation) erasers of DNA methylation.1,2 TET2 is frequently mutated in myeloid neoplasms - TET2 inhibition with TETi76 res