iPHF8 is a specific inhibitor (IC50 = 2.01 µM, EC50 = 2 µM in HeLa cells) of the human non-heme 2-oxoglutarate JmjC domain oxygenase/lysine demethylase PHF8. PHF8 also demethylates the transcription factor YY1 acting as a co-repressor for many electron t
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