Raltitrexed, CAS [[112887-68-0]]

Product Overview

• Article Name: Raltitrexed, CAS [[112887-68-0]]
• Biozol Catalog Number: FBM-10-4052
• Supplier Catalog Number: 10-4052
• Alternative Catalog Number: FBM-10-4052-10MG,FBM-10-4052-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: ICI D 1694, ZD1694

Product Description

Thymidylate synthase inhibitor

Product Properties

• Molecular Weight: 458.49
• Purity: >98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [112887-68-0]
• Formula: C21H22N4O6S

Application Notes

• Application Notes: Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased Aß aggregates in C