A-438079 HCl, CAS [[899431-18-6]]

Product Overview

• Article Name: A-438079 HCl, CAS [[899431-18-6]]
• Biozol Catalog Number: FBM-10-4063
• Supplier Catalog Number: 10-4063
• Alternative Catalog Number: FBM-10-4063-5MG,FBM-10-4063-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

P2X7 antagonist

Product Properties

• Molecular Weight: 342.61
• Purity: 98% by HPLC NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [899431-18-6]
• Formula: C13H9Cl2N5 HCl

Application Notes

• Application Notes: A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1ß and attenuated LPS-induced (via intrathecal lumbar