ML277, CAS [[1401242-74-7]]

Product Overview

• Article Name: ML277, CAS [[1401242-74-7]]
• Biozol Catalog Number: FBM-10-4074
• Supplier Catalog Number: 10-4074
• Alternative Catalog Number: FBM-10-4074-5MG,FBM-10-4074-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: (R)-N-(4-(4-Methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide

Product Description

Potent Kv7.1 activator

Product Properties

• Molecular Weight: 471.59
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1401242-74-7]
• Formula: C23H25N3O4S2

Application Notes

• Application Notes: ML277 is a potent (EC50 = 260 nM) activator of Kv7.1 with selectivity against Kv7.2, Kv7.4, and Kv11.1 (hERG).1 ML277 enhances cardiac delayed rectifier K+ currents (IKs) in human iPSC-derived cardiomyocytes from normal and long QT-interval syndrome affl