CPI-444, CAS [[1202402-40-1]]

Product Overview

• Article Name: CPI-444, CAS [[1202402-40-1]]
• Biozol Catalog Number: FBM-10-4101
• Supplier Catalog Number: 10-4101
• Alternative Catalog Number: FBM-10-4101-5MG,FBM-10-4101-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Ciforadenant

Product Description

Adenosine A2A receptor antagonist

Product Properties

• Molecular Weight: 407.43
• Purity: 98% by HPLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [1202402-40-1]
• Formula: C20H21N7O3

Application Notes

• Application Notes: CPI-444 (1202402-40-1) is a potent (Ki = 3.54 nM) and selective adenosine A2A receptor antagonist. It blocked the induction of cAMP induced by NECA in HEK-293 cells with an IC50 = 17.03 nM. CPI-444 monotherapy or in combination with anti-PD-1, anti-PD-L1