Galunisertib, CAS [[700874-72-2]]

Product Overview

• Article Name: Galunisertib, CAS [[700874-72-2]]
• Biozol Catalog Number: FBM-10-4110
• Supplier Catalog Number: 10-4110
• Alternative Catalog Number: FBM-10-4110-5MG,FBM-10-4110-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: LY2157299

Product Description

TGFß receptor 1 inhibitor / Cancer immunotherapeutic

Product Properties

• Molecular Weight: 369.43
• Purity: 98%, NMR (Conforms)
• Form: White solid
• CAS Number: [700874-72-2]
• Formula: C22H19N5O

Application Notes

• Application Notes: Galunisertib is a TGF-B kinase (ALK5) antagonist.1 It stimulated hematopoiesis from primary myelodysplastic syndrome bone marrow specimens via downregulation of SMAD2 phosphorylation.2 It has been in clinical trials for treatment of various cancers.3-5 G