THZ1, CAS [[1604810-83-4]]

Product Overview

• Article Name: THZ1, CAS [[1604810-83-4]]
• Biozol Catalog Number: FBM-10-4120
• Supplier Catalog Number: 10-4120
• Alternative Catalog Number: FBM-10-4120-5MG,FBM-10-4120-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

CDK7 inhibitor

Product Properties

• Molecular Weight: 566.05
• Purity: 97% by HPLC
• Form: Tan solid
• CAS Number: [1604810-83-4]
• Formula: C31H28ClN7O2

Application Notes

• Application Notes: THZ1 is an irreversible, covalent inhibitor (dual ATP-site and allosteric covalent binding) of CDK7 (IC50 = 15.6nM 20min and 3.2nM 180 min).1 It displayed broad based antiproliferative activity with IC50s of less than 200nM against 53% of the 1000 c