I-BET762, CAS [[1260907-17-2]]

Product Overview

• Article Name: I-BET762, CAS [[1260907-17-2]]
• Biozol Catalog Number: FBM-10-4122
• Supplier Catalog Number: 10-4122
• Alternative Catalog Number: FBM-10-4122-5MG,FBM-10-4122-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: GSK525762

Product Description

BET bromodomain inhibitor / Supresses Myc transcription

Product Properties

• Molecular Weight: 423.90
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Tan solid
• CAS Number: [1260907-17-2]
• Formula: C22H22ClN5O2

Application Notes

• Application Notes: I-BET762 is a potent inhibitor of the BET family of bromodomains with no activity at bromodomains BAZ2B, SP140, ATAD2, CREBBO, and PCAF.1,2 IC50s for H4Ac peptide displacement: BRD2 = 32.5nM, BRD3 = 42.4nM, BRD4 = 36.1nM.1 It was able to suppress proinf