Alisertib, CAS [[1028486-01-2]]

Product Overview

• Article Name: Alisertib, CAS [[1028486-01-2]]
• Biozol Catalog Number: FBM-10-4124
• Supplier Catalog Number: 10-4124
• Alternative Catalog Number: FBM-10-4124-5MG,FBM-10-4124-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: MLN8237

Product Description

Aurora A inhibitor, Destablizes Myc

Product Properties

• Molecular Weight: 518.92
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1028486-01-2]
• Formula: C27H20ClFN4O4

Application Notes

• Application Notes: Alisertib (MLN8237) is a highly selective and potent (IC50 = 1 nM) cell permeable inhibitor of Aurora A with off-target binding at GABAA (IC50 = 490 nM).1 It disrupts the Aurora A-Myc complex leading to Myc degradation2 in Myc amplified neuroblastomas3 a