P22077, CAS [[1247819-59-5]]

Product Overview

• Article Name: P22077, CAS [[1247819-59-5]]
• Biozol Catalog Number: FBM-10-4125
• Supplier Catalog Number: 10-4125
• Alternative Catalog Number: FBM-10-4125-10MG,FBM-10-4125-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

USP7 inhibitor

Product Properties

• Molecular Weight: 315.32
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1247819-59-5]
• Formula: C12H7F2NO3S2

Application Notes

• Application Notes: P22077 is a selective (tested against 23 other DUBs) inhibitor of USP7 (IC50 = 8 µM) and the closely related USP47.1,2 It destabilizes claspin, a scaffolding protein involved in regulating Chk1 kinase, a DNA damage response enzyme.2 P22077 inhibits neuro