RO-3306, CAS [[872573-93-8]]

Product Overview

• Article Name: RO-3306, CAS [[872573-93-8]]
• Biozol Catalog Number: FBM-10-4126
• Supplier Catalog Number: 10-4126
• Alternative Catalog Number: FBM-10-4126-5MG,FBM-10-4126-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

CDK1 inhibitor

Product Properties

• Molecular Weight: 351.45
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white or pale yellow solid
• CAS Number: [872573-93-8]
• Formula: C18H13N3OS2

Application Notes

• Application Notes: RO-3306 is a selective inhibitor of CDK1 (IC50 = 35 nM versus CDK2 IC50 = 340nM).1,2 It induces G2/M phase cell cycle arrest and apoptosis. Inhibition of CDK1 with RO-3306 has been shown to have synergistic effects with PARP inhibitors in treating variou