GSK2830371, CAS [[1404456-53-6]]

Product Overview

• Article Name: GSK2830371, CAS [[1404456-53-6]]
• Biozol Catalog Number: FBM-10-4180
• Supplier Catalog Number: 10-4180
• Alternative Catalog Number: FBM-10-4180-5MG,FBM-10-4180-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

WIP1 phosphatase inhibitor

Product Properties

• Molecular Weight: 461.02
• Purity: 97% by HPLC NMR (Conforms)
• Form: Tan solid
• CAS Number: [1404456-53-6]
• Formula: C23H29ClN4O2S

Application Notes

• Application Notes: Potent allosteric inhibitor of WIP1 phosphatase (IC50 = 6 nM), a negative regulator of the DNA damage response.1 It displayed no inhibition of 21 other phosphatases. Active in xenograft model DoHH2 B-cell lymphoma. GSK2830371 in combination with MDM2 inh