DS18561882, CAS [[2227149-22-4]]

Product Overview

• Article Name: DS18561882, CAS [[2227149-22-4]]
• Biozol Catalog Number: FBM-10-4188
• Supplier Catalog Number: 10-4188
• Alternative Catalog Number: FBM-10-4188-5MG,FBM-10-4188-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: DS18

Product Description

MTHFD2 inhibitor

Product Properties

• Molecular Weight: 608.63
• Purity: >98% by HPLC NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [2227149-22-4]
• Formula: C28H31F3N4O6S

Application Notes

• Application Notes: Potent (IC50 = 6.3 nM) and selective (>90-fold over MTHFD1) inhibitor of the mitochondrial enzyme methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a key enzyme in one carbon metabolism in purine or thymidine biosynthesis.1 It almost completely inhibit