L-755,507 is a very potent (EC50 = 0.43 nM, IC50 = 13 nM) human ß3 adrenergic receptor agonist with >440-fold selectivity of ß1/2.1 It elicited lipolysis and metabolic rate elevation in rhesus monkeys.2 L-755,507 has been shown to increase homology-direc
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