Maraviroc, CAS [[376348-65-1]]
Catalog Number:
FBM-10-4260
Article Name: |
Maraviroc, CAS [[376348-65-1]] |
Biozol Catalog Number: |
FBM-10-4260 |
Supplier Catalog Number: |
10-4260 |
Alternative Catalog Number: |
FBM-10-4260-5MG,FBM-10-4260-25MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Alternative Names: |
UK-427,857 |
Molecular Weight: |
513.68 |
Purity: |
>98% by HPLC NMR (Conforms) |
Form: |
White solid |
CAS Number: |
[376348-65-1] |
Formula: |
C29H41F2N5O |
Application Notes: |
Potent and selective CCR5 antagonist with potent anti-HIV activity. It prevents HIV-1 gp120 binding to CCR5 preventing cell-cell fusion. Maraviroc inhibited MIP-1a (IC50 = 3.3 nM), MIP-1b (IC50 = 7.2 nM), and RANTES (IC50 = 5.2 nM) binding to CCR5-expres |