Maraviroc, CAS [[376348-65-1]]

Catalog Number: FBM-10-4260
Article Name: Maraviroc, CAS [[376348-65-1]]
Biozol Catalog Number: FBM-10-4260
Supplier Catalog Number: 10-4260
Alternative Catalog Number: FBM-10-4260-5MG,FBM-10-4260-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: UK-427,857
CCR5 antagonist
Molecular Weight: 513.68
Purity: >98% by HPLC NMR (Conforms)
Form: White solid
CAS Number: [376348-65-1]
Formula: C29H41F2N5O
Application Notes: Potent and selective CCR5 antagonist with potent anti-HIV activity. It prevents HIV-1 gp120 binding to CCR5 preventing cell-cell fusion. Maraviroc inhibited MIP-1a (IC50 = 3.3 nM), MIP-1b (IC50 = 7.2 nM), and RANTES (IC50 = 5.2 nM) binding to CCR5-expres