BI 749327, CAS [[2361241-23-6]]

Product Overview

• Article Name: BI 749327, CAS [[2361241-23-6]]
• Biozol Catalog Number: FBM-10-4318
• Supplier Catalog Number: 10-4318
• Alternative Catalog Number: FBM-10-4318-5MG,FBM-10-4318-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Selective TRPC6 antagonist

Product Properties

• Molecular Weight: 442.44
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [2361241-23-6]
• Formula: C23H21F3N4O2

Application Notes

• Application Notes: Potent (IC50 = 13 nM mouse TRPC6, 19 nM human TRPC6) and selective (85-fold over TRPC3, 42-fold over TRC7) orally available blocker of TRPC6.1 It suppressed interstitial fibrosis and associated molecular signaling in mouse heart and kidney disease models