Buparlisib, CAS [[944396-07-0]]

Product Overview

• Article Name: Buparlisib, CAS [[944396-07-0]]
• Biozol Catalog Number: FBM-10-4325
• Supplier Catalog Number: 10-4325
• Alternative Catalog Number: FBM-10-4325-5MG,FBM-10-4325-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: NVP-BKM120, BKM-120

Product Description

PI3-kinase inhibitor

Product Properties

• Molecular Weight: 410.39
• Purity: 99% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [944396-07-0]
• Formula: C18H21F3N6O2

Application Notes

• Application Notes: Potent pan-Class I PI3-kinase inhibitor (IC50s: p110alpha = 52 nM, p110ß = 166 nM, p110delta = 116 nM. P110g = 262 nM).1,2 It inhibited microtubule dynamics at in vitro concentrations >1µM and doses above 50mg/kg in mice.3 Buparlisib lead to a precipitous drop