Icilin, CAS [[36945-98-9]]

Product Overview

• Article Name: Icilin, CAS [[36945-98-9]]
• Biozol Catalog Number: FBM-10-4380
• Supplier Catalog Number: 10-4380
• Alternative Catalog Number: FBM-10-4380-10MG,FBM-10-4380-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: AG 3-5

Product Description

TRPM8 inhibitor

Product Properties

• Molecular Weight: 311.29
• Purity: >98% by TLC [5% methanol in methylene chloride, Rf = 0.40]
• Form: Yellow solid
• CAS Number: [36945-98-9]
• Formula: C16H13N3O4

Application Notes

• Application Notes: Icilin is an agonist of cold-sensitive TRP channels with 2.5-fold greater efficacy and 200-fold greater potency than menthol (EC50 = 0.36 µM for CRM1, rat orthologue of TRPM8).1 Agonist at TRPM8 (EC50 = 0.2 µM)2 and ANKTM1(TRPA1)3. Agonist effects requir