Prodrug of VRT-043198, a potent (Ki = 0.8 nM ICE/caspase-1, <0.6nM caspase-4) and selective inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases.1 VRT-043198 ICE/caspase-1 IC50 = 0.67 µM PBMCs, 1.0 µM whole blood. It inhibited the rele
* VAT and and shipping costs not included. Errors and price changes excepted