SBI-553, CAS [[1849603-72-0]]

Product Overview

• Article Name: SBI-553, CAS [[1849603-72-0]]
• Biozol Catalog Number: FBM-10-4449
• Supplier Catalog Number: 10-4449
• Alternative Catalog Number: FBM-10-4449-5MG,FBM-10-4449-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

ß-Arrestin-biased NTSR1 modulator

Product Properties

• Molecular Weight: 450.56
• Purity: >98% by HPLC NMR (conforms)
• Form: Pale yellow solid
• CAS Number: [1849603-72-0]
• Formula: C26H31FN4O2

Application Notes

• Application Notes: SBI-553 is a potent, brain penetrant, and orally bioavailable allosteric modulator of neurotensin receptor 1 (NTSR1, EC50 = 340 nM)).1 It acts as a ß-Arrestin-biased agonist and selectively antagonizes G protein signaling conferring profound ß-Arrestin b